LONDON — Chelsea manager Antonio Conte declared his side's Premier League title defense over after Marko Arnautovic's goal condemned the champions to a 1-0 defeat at West Ham United on Saturday.

Chelsea's defeat, their first in eight league games, left them 11 points adrift of leaders Manchester City, who visit second-placed Manchester United in Sunday's Manchester derby.

We have to consider that this is the fourth game we've lost in 16 games, Conte told Sky Sports at the London Stadium. In my previous experience, it won't be possible to fight for the title. With four defeats in 16 games, we must have another target.

Elsewhere, Tottenham Hotspur ended a run of four games without victory with a thumping 5-1 home win over Stoke City at Wembley in which Harry Kane scored twice.

Having previously been beaten by Burnley, Manchester City and Crystal Palace, Chelsea have lost just one fewer game than in the entirety of their triumphant 2016-17 campaign.

Austria international Arnautovic struck in the sixth minute, neatly exchanging passes with Manuel Lanzini and cutting inside Cesar Azpilicueta before curling a low shot past Thibaut Courtois.

Alvaro Morata squandered Chelsea's best chance of an equalizer when he slashed wide from N'Golo Kante's through ball with seven minutes remaining.

It was West Ham's first win in nine league games and confirmed the progress they have made under new manager David Moyes, who saw his side narrowly beaten 2-1 at Manchester City last weekend.

The win, the spirit of the team, how they stuck together and more importantly a lot of the basics were done well today, said Moyes. All that really pleased me.

West Ham remain in the relegation zone, but they are now level on points with fourth-bottom West Bromwich Albion, who lost 1-0 at Swansea City in Alan Pardew's second game as manager. Wilfried Bony scored for the second game running to lift Swansea off the foot of the table.

Spurs claimed a fourth successive four-goal win over Stoke, making Mauricio Pochettino's side the first team to have won by four goals in four consecutive English top-flight meetings with the same opponents.

Son Heung-Min's cross was deflected in via Stoke defenders Kurt Zouma and Ryan Shawcross to put Spurs ahead and Son made it 2-0 by rattling in a pass from Dele Alli in the 53rd minute.

Kane's two goals — a header from a Ben Davies cross and a left-foot curler — took his tally for the season to 18 in all competitions and Christian Eriksen completed the rout.

Stoke, who replied through Shawcross, have now lost 1,000 top-flight games. Spurs moved above Arsenal into fifth place on goal difference ahead of their local rivals' trip to Southampton on Sunday.

Burnley are level on points with the two north London heavyweights after Scott Arfield scored in a 1-0 home win over Watford, who had Marvin Zeegelaar sent off for a studs-up foul on Steven Defour.

Crystal Palace fell to the foot of the table after Belgian striker Christian Benteke squandered a stoppage-time penalty in a 2-2 draw at home to Bournemouth.

Jermain Defoe put Bournemouth in front and then equalised with a brilliant dipping volley after Luka Milivojevic's penalty and a close-range effort by substitute Scott Dann had put Palace in charge.

Palace were awarded a last-gasp penalty when Charlie Daniels felled Wilfried Zaha, but Benteke's tame effort was repelled by visiting goalkeeper Asmir Begovic.

Steve Mounie's first goals since the opening day earned Huddersfield Town a 2-0 win over fellow promoted team Brighton and Hove Albion as David Wagner's side snapped a four-game losing streak.

In-form Leicester City visit Newcastle United in the day's late game.

Meanwhile, a goal in stoppage time by Aden Flint gave Bristol City a 2-1 win over 10-man Sheffield United in an enthralling match in the English Championship on Friday.

Flint's sixth goal of the season —the most for a defender in England's second tier this term — sent City three points clear of United in third place and seven behind leaders Wolves, who host struggling Sunderland on Saturday.

Jamie Paterson had given the visitors the lead at Bramall Lane against the run of play in the first half, only for veteran striker Leon Clarke to level early in the second half with a league-leading 14th of the campaign.

City — who were embroiled in a relegation battle last season — are unbeaten in 10 away matches now.

United, who have not won in four, could count themselves unlucky, hitting the woodwork four times. They were in the ascendancy when John Fleck was shown a straight red by referee David Coote for a two-footed challenge in the 59th minute.

The Blades should have been well ahead before Paterson struck three minutes from half-time as Mark Duffy and Billy Sharp were denied by the woodwork and both also saw goal-bound efforts brilliantly saved by Frank Fielding.

However, they were hit on the break as a lovely move finished off by a sublime right-footed curling effort by Paterson gave the visitors the lead.

United, though, struck back early in the second half, Clarke running at the defense before the 32-year-old — at his 18th different club — unleashed a fierce strike from the edge of the area to beat Fielding at last. Duffy — who dropped out of the game at one point to be a scaffolder before fighting his way back up from non-league football — went close to giving United the lead but once again the woodwork denied him.

However, Fleck's loss of control shortly afterwards swung the game away from the Blades. United defied City for almost half an hour until their concentration slipped in the dying minutes and Flint nipped in and rifled the ball home. — AFP