CLEVELAND — Carlos Santana belted a walk-off solo homer with one out in the ninth inning as the Cleveland Indians beat the visiting Toronto Blue Jays 3-2 Friday.

After Jake Bauers flied out to begin the ninth inning, Santana deposited a 1-0 fastball from Joe Biagini (0-1) into the bleachers in left-center field. The blast was Santana’s fifth career walk-off homer and Cleveland’s first walk-off win of the season.

Kevin Plawecki launched a homer to lead off the third inning and Max Moroff had an RBI double in the fifth for the Indians. Freddy Galvis belted a two-run homer in the fifth inning for the Blue Jays, who mustered just three hits for the second straight night and have lost five of their past six games overall.

Adam Cimber (1-0) picked up the win after pitching a scoreless top of the ninth.

Phillies 10, Twins 4

Rhys Hoskins had three hits and drove in four runs, and Odubel Herrera also had three hits as host Philadelphia overcame a five-hit cycle by Minnesota’s Jorge Polanco.

Polanco tripled in the first, singled in the third, lined a homer in the fifth and then doubled to left in the seventh for the 11th cycle in Twins’ history and the first since Michael Cuddyer did it on May 22, 2009. Polanco also singled in the ninth to finish 5-for-5 for the second five-hit cycle in franchise history, joining Joe Cronin, who did it on Sept. 2, 1929, with the Washington Senators.

Maikel Franco doubled and drove in two runs, and Jean Segura had two hits, scored twice and also drove in a run for the Phillies, who also took advantage of nine walks and two hit batters by Minnesota pitchers.

Angels 3, Rangers 1

Mike Trout’s leadoff home run in the sixth inning snapped a tie, and two innings later he added another homer, lifting Los Angeles past Texas in Anaheim, Calif.

Trout’s home runs, his third in the past two nights, marked the 15th multi-homer game of his career. The first came on a 2-0 fastball from Rangers starter Lance Lynn, who otherwise pitched a solid game. Lynn (0-1) gave up two runs on five hits in seven innings. He struck out five and walked one.

Trout gave Angels closer Cody Allen a little extra cushion with his homer off Jesse Chavez in the eighth. Allen pitched a 1-2-3 ninth for his first save. Angels reliever Justin Anderson (1-0) earned the victory with 1 1/3 scoreless innings.

Brewers 13, Cubs 10

Ryan Braun finished with four RBIs and was one of five Milwaukee batters to homer, and the Brewers held on for a win over visiting Chicago.

Hernan Perez, Yasmani Grandal, Orlando Arcia and Eric Thames also belted homers for the Brewers, who scored the first eight runs. Milwaukee increased its winning streak to six games.

Daniel Descalso, Willson Contreras and Jason Heyward homered for Chicago, which has dropped six in a row since winning its season opener. The Cubs have given up 55 runs during their skid -- an average of 9.2 runs per game.

Braves 4, Marlins 0

Ronald Acuna Jr. hit his second homer of the season to start a four-run fourth-inning rally, and Atlanta defeated visiting Miami for its fourth consecutive win.

Acuna, the 2018 National League Rookie of the Year, now has eight home runs in 20 career games against the Marlins. The left fielder is hitting .337 (26-for-77) with 20 RBIs against Miami.

The winning pitcher was Kevin Gausman (1-0), who made his season debut after dealing with some shoulder inflammation in spring training. He worked efficiently, throwing only 88 pitches in seven shutout innings and retiring 13 straight Marlins at one point.

Diamondbacks 15, Red Sox 8

Ketel Marte hit two home runs, including a grand slam, and Adam Jones, Ildemaro Vargas and Alex Avila also belted homers in Arizona’s win over Boston at Phoenix.

Dodgers 10, Rockies 6

Cody Bellinger and Max Muncy each homered and drove in three runs, Russell Martin also homered, and hot-hitting Los Angeles beat Colorado in Denver.

Padres 5, Cardinals 3

Fernando Tatis Jr. capped a three-run seventh inning with a two-run homer, leading San Diego to a victory at St. Louis in the Cardinals’ home opener.

White Sox 10, Mariners 8

Yoan Moncada had two hits and four RBIs, including a go-ahead two-run single in the seventh inning, to lead Chicago past Seattle in the White Sox’s home opener.

Pirates 2, Reds 0

Jung Ho Kang’s seventh-inning RBI double broke up an intense pitchers’ duel as Pittsburgh beat visiting Cincinnati, the Reds’ sixth straight loss and third in a row by shutout.

Rays 5, Giants 2

Tampa Bay scored four runs before many at San Francisco’s home opener had settled in, and Tyler Glasnow pitched six innings of three-hit, shutout ball in the Rays’ victory.

Astros 3, A’s 2

Collin McHugh worked six strong innings, Carlos Correa clubbed his first home run, and Houston won its home opener, beating Oakland. — Reuters