NEW YORK — Roberto Perez homered in his fourth straight game and drove in three runs as the host Cleveland Indians denied CC Sabathia in his bid for his 250th career win with an 8-4 victory over the New York Yankees on Saturday.

Rookie Oscar Mercado launched a two-run homer and Kevin Plawecki added a solo shot and a sacrifice fly for the Indians, who have belted 14 homers while winning four of their past five games.

The offense was more than enough for Adam Plutko (2-1), who overcame Didi Gregorius' two-run homer in the first to allow just two runs on three hits in six innings. Oliver Perez permitted two runs on as many hits, but three other relievers combined to yield one hit over the final 2 2/3 scoreless innings to end the game.

Gleyber Torres had an RBI double and scored on a sacrifice fly in the seventh inning for the Yankees, who have lost five of their past six games.

Angels 12, Mariners 3

Los Angeles hit back-to-back-to-back home runs in the fourth inning and cruised past visiting Seattle.

Tommy La Stella, Mike Trout and Shohei Ohtani went deep off Mariners left-hander Yusei Kikuchi (3-4) in the fourth. Cesar Puello, who finished with four RBIs, homered in the eighth for the Angels.

It was Ohtani's first showdown with Kikuchi in the United States and drew widespread interest in their native Japan, where they attended the same high school. The two faced each other five times in Nippon Professional Baseball, with Ohtani going 2-for-5 with a double and three strikeouts.

Cubs 9, Cardinals 4

Victor Caratini delivered a pinch-hit, tiebreaking, three-run double in the sixth inning, and host Chicago pulled away for a win over St. Louis.

Kyle Schwarber doubled, homered and drove in two runs for the Cubs, while Javier Baez finished with a triple and two RBIs. Chicago fell behind 4-0 in the first inning but scored the next nine runs to notch its fifth victory in the past six games.

Marcell Ozuna and Harrison Bader homered for St. Louis, which dropped back to .500 with its third loss in the past four games. The Cardinals fell to 0-5 at Wrigley Field this season.

Phillies 4, Reds 1

Nick Pivetta pitched his first career complete game, J.T. Realmuto homered and Philadelphia beat visiting Cincinnati for its fourth straight win.

Coming off six scoreless innings against the Los Angeles Dodgers in his previous outing, Pivetta allowed a run on six hits and no walks while striking out six. He had never previously gone beyond 7 1/3 innings.

Pivetta (4-1) allowed hits to the first two Reds batters and then didn't allow another baserunner until Joey Votto's leadoff single in the seventh inning.

Dodgers 7, Giants 2

Corey Seager had four hits and four RBIs to lift Los Angeles over host San Francisco.

Seager finished 4-for-5 with a pair of doubles and has hits in 13 of his last 14 games. Justin Turner, who was questionable to play because of a tight hamstring, went 3-for-3 with two doubles, two runs and two RBIs.

Los Angeles starter Rich Hill (3-1) earned the win with five innings of two-run ball, allowing seven hits, walking three and striking out six.

Rays 9, Red Sox 2 (Game 1)

Ryan Yarbrough pitched a career-high 7 2/3 superb innings, and Travis d'Arnaud backed him with a three-run homer as visiting Tampa Bay once again stymied Boston's bats in a win to kick off a day-night doubleheader.

Yarbrough (5-2) gave up the two runs (one earned) on four hits and struck out seven as the Rays won their fourth straight to tie the New York Yankees atop the American League East standings.

The Red Sox, who lost 5-1 Friday after entering the series outscoring opponents 31-13 over a four-game winning streak, were kept to one run until Jackie Bradley Jr. homered in the eighth. Star slugger J.D. Martinez was again sidelined by back spasms.

Red Sox 5, Rays 1

David Price matched his season high with 10 strikeouts over six innings as Boston beat visiting Tampa Bay to salvage a split of a day-night doubleheader.

Price (4-2) played stopper yet again after the Red Sox lost the first two of the four-game series. He gave up one run on five hits and walked two, recording seven of his strikeouts against the Nos. 3-5 hitters in the Rays lineup.

Tampa Bay had a four-game winning streak come to an end. As part of a bullpen game, Colin Poche (0-1) took the loss in his major league debut.

White Sox 2, Royals 0

Lucas Giolito outdueled Brad Keller, posting a career-high 11 strikeouts, as Chicago defeated host Kansas City.

Giolito didn't give up his first hit until a lead-off single in the fourth by Alex Gordon. At one stretch, he got eight straight outs via the strikeout. He matched his career high of 10 strikeouts with two outs in the fifth inning. He broke it with his third strikeout of that inning.

The victory for Chicago set up a rubber game for the series on Sunday, a contest that hasn't gone well for the Royals. They are 0-5 in rubber games in 2019 and 0-13 in rubber games dating back to May 30, 2018.

Brewers 5, Pirates 3

Ryan Braun produced a tiebreaking single in the fourth inning, and Milwaukee continued its success over visiting Pittsburgh.

The Brewers moved to a season-high nine games over .500, won for the eighth time in 12 games and improved to 5-1 against the Pirates on a day in which they stranded 13 and went 2-for-14 with runners in scoring position.

Braun, who hit a three-run homer in Friday's 10-4 win, snapped a 3-3 tie when he lined a single to center field off Michael Feliz (2-2) to score Lorenzo Cain. Mike Moustakas homered, Orlando Arcia had an RBI double and Cain produced a run-scoring single for the Brewers.

Orioles 4, Astros 1

Andrew Cashner worked six solid innings, Anthony Santander produced a sparkling defensive play, and Trey Mancini scored the go-ahead run on an error in the eighth inning as Baltimore scratched out a victory over host Houston.

The Orioles will go for the series victory Sunday in the rubber match. Baltimore is 0-11-1 in its last 12 series, while the Astros are 9-0-1 over their last 10.

Left-hander Paul Fry (1-3) earned the win in relief for the Orioles. Miguel Castro notched his second save.

Braves 1, Marlins 0

Julio Teheran pitched six scoreless innings, and rookie Austin Riley doubled and scored the game's only run as Atlanta defeated host Miami.

Luke Jackson got four outs for his ninth save of the season, as the Braves have won 18 of their past 22 games against the Marlins, including the first two contests in this series.

For Teheran (4-4, 3.03 ERA), this was the third time this year he has pitched at least five scoreless innings. He allowed just two hits — one single and one double — walked one and struck out five. He got eight ground-ball outs and three flyouts.

Tigers 9, Twins 3

JaCoby Jones homered twice and drove in five runs, and Christin Stewart also homered to lead Detroit to victory over visiting Minnesota.

Jones finished 3-for-4 and also scored two runs while Miguel Cabrera, Gordon Beckham, Brandon Dixon and Harold Castro each added two hits for Detroit, which snapped a three-game losing streak and won for just the second time in its last 15 home games.

Nick Ramirez (2-0), the second of five Detroit pitchers, picked up the victory, allowing one run on three hits and three walks over three innings. He struck out three.

Mets 5, Rockies 3

Carlos Gomez and Pete Alonso homered, Steven Matz tossed six solid innings, and host New York beat Colorado.

Gomez, Todd Frazier and Wilson Ramos had two hits each, and Edwin Diaz pitched the ninth for his 14th save for the Mets.

Nolan Arenado and Charlie Blackmon had RBIs for the Rockies, who fell to 2-3 on their six-game road trip.

Nationals 4, Padres 1

Max Scherzer allowed six hits over seven shutout innings, and Brian Dozier hit a two-run homer for his 1,000th career hit as visiting Washington won at San Diego after two straight losses.

Scherzer improved to 4-5 and lowered his ERA to 2.82. He issued one walk and struck out nine while throwing 101 pitches. Over his last four starts, Scherzer has given up two runs on 20 hits and five walks with 39 strikeouts in 27 innings.

Scherzer allowed more than one hit in only one inning against San Diego, with only three Padres advancing into scoring position.

Diamondbacks 6, Blue Jays 0

Zack Greinke pitched six-plus innings, Alex Avila and Kevin Cron homered and visiting Arizona defeated Toronto.

Greinke (7-2) held the Blue Jays to four hits and two walks and had seven strikeouts. It was his first win since May 15, a span of three winless starts that included one loss.

The Diamondbacks have won the first two games of the three-game series — and have won three straight overall — and will go for the sweep Sunday afternoon. Rangers 10, A's 5 (Game 1)

Tim Federowicz hit a three-run homer one day after being acquired in a trade, helping Texas break open a close game en route to victory over Oakland in the first game of a doubleheader in Arlington, Texas.

Nomar Mazara drove in three runs, two with a homer, and Asdrubal Cabrera had a two-run single for the Rangers, who were beaten 5-3 by the A's in the opener of the four-game series on Friday night.

Jeffrey Springs (4-1) was credited with the win after pitching three innings of one-run relief.

Rangers 3, A's 1 (Game 2)

Right-hander Adrian Sampson dominated Oakland with the first complete game of his career, helping Texas complete a day/night sweep in Arlington.

Sampson (5-3) won his fifth consecutive start with a brilliant effort, holding the A's to one run on four hits. He walked one, struck out seven and retired the last 12 batters he faced. He threw a career-high 109 pitches.

The 27-year-old with no wins in two previous seasons and no previous start longer than seven innings has allowed just seven runs in 31 2/3 innings during his 5-0 run. — Reuters